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In Situ Remodeling Overrules Bioinspired Scaffold Architecture of Supramolecular Elastomeric Tissue-Engineered Heart Valves

Uiterwijk M, Smits AIPM, van Geemen D, van Klarenbosch B, Dekker S, Cramer MJ, van Rijswijk JW, Lurier EB, Di…

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Heart Valve Disease: Challenges and New Opportunities

Bartoli-Leonard F, Aikawa E. Front Cardiovasc Med. 2020 Oct 22;7:602271. PMID: 33195488. PMC7642276. View Article

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An (Auto)Taxing Effort to Mechanistically Link Obesity and Calcific Aortic Valve Disease

Rogers MA, Aikawa E. JACC Basic Transl Sci. 2020 Sep 28;5(9):898-900. PMID: 33016951. PMC7524779. View Article

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Annexin A1-dependent Tethering Promotes Extracellular Vesicle Aggregation Revealed with Single-Extracellular Vesicle Analysis

Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K,…

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Innate and Adaptive Immunity in Cardiovascular Calcification

Passos LSA, Lupieri A, Becker-Greene D, Aikawa E. Atherosclerosis. 2020 Aug;306:59-67. Review. PMID: 32222287. PMC7483874. View Article

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Complex Association of Lipoprotein(a) with Aortic Stenosis

Rogers MA, Aikawa E. Heart. 2020 May;106(10):711-2. PMID: 32086294. View Article

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Retinoids Repress Human Cardiovascular Cell Calcification with Evidence for Distinct Selective Retinoid Modulator Effects

Rogers MA, Chen J, Nallamshetty S, Pham T, Goto S, Muehlschlegel JD, Libby P, Aikawa M, Aikawa E, Plutzky J. Arterioscler…

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Harnessing Single-Cell RNA Sequencing to Better Understand How Diseased Cells Behave the Way They Do in Cardiovascular Disease

Iqbal F, Lupieri A, Aikawa M, Aikawa E. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):585-600. PMID: 33327741. PMC8105278. View Article

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Valve under the Microscope: Shining a Light on Emerging Technologies Elucidating Disease Mechanisms

Atkins SK, Aikawa E. Heart. 2019 Nov;105(21):1610-1. PMID: 31296591. PMC6855786. View Article

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Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification

Goto S, Rogers MA, Blaser MC, Higashi H, Lee LH, Schlotter F, Body SC, Aikawa M, Singh SA, Aikawa E. Front…

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Mitral Valve Adaptation to Isolated Annular Dilation: Insights Into the Mechanism of Atrial Functional Mitral Regurgitation

Kim DH, Heo R, Handschumacher MD, Lee S, Choi YS, Kim KR, Shin Y, Park HK, Bischoff J, Aikawa E,…

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18F-Fluoride Signal Amplification Identifies Microcalcifications Associated with Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed Tomography Images

Creager MD, Hohl T, Hutcheson JD, Moss AJ, Schlotter F, Blaser MC, Park MA, Lee LH, Singh SA, Alcaide-Corral CJ,…

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