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  • CAVD occurs in >25% individuals over 65 yo
  • Overall prevalence of 2.5% for any valve disease
  • Poor prognosis (heart failure; 50% will not survive more than 2 years after onset of  symptoms; predicted survival of inoperable patients is lower than with metastatic cancers)
  • Bicuspid aortic valve is the most common congenital cardiovascular defect
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