CardioVision: A Fully Automated Deep Learning Package for Medical Image Segmentation and Reconstruction Generating Digital Twins for Patients With Aortic Stenosis
Rouhollahi A, Willi JN, Haltmeier S, Mehrtash A, Straughan R, Javadikasgari H, Brown J, Itoh A, de la Cruz KI,…
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves
Ho YC, Geng X, O'Donnell A, Ibarrola J, Fernandez-Celis A, Varshney R, Subramani K, Azartash-Namin ZJ, Kim J, Silasi R,…
Multimodal Analytical Tools to Enhance Mechanistic Understanding of Aortic Valve Calcification
Perez KA, Deppe DW, Filas A, Singh SA, Aikawa E. Am J Pathol. 2023 Jul 28:S0002-9440(23)00270-5. PMID: 37517686. View Article
Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis
Blaser MC, Buffolo F, Halu A, Turner ME, Schlotter F, Higashi H, Pantano L, Clift CL, Saddic LA, Atkins SK,…
Single-Cell T Cell Receptor Sequencing of Paired Tissue and Blood Samples Reveals Clonal Expansion of CD8+ Effector T Cells in Patients With Calcific Aortic Valve Disease
Bartoli-Leonard F, Chelvanambi S, Pham T, Turner ME, Blaser MC, Caputo M, Aikawa M, Pang A, Muehlschlegel J, Aikawa E.…
Editorial: New Insights in Heart Valve Disease 2022
Greco E, Vinciguerra M, Sampaio R, Aikawa E. Front Cardiovasc Med. 2023 Jun 21;10:1226113. PMID: 37416925. PMC10321655. View Article
The Contribution of Amyloid Deposition in the Aortic Valve to Calcification and Aortic Stenosis
Sud K, Narula N, Aikawa E, Arbustini E, Pibarot P, Merlini G, Rosenson RS, Seshan SV, Argulian E, Ahmadi A,…
Editorial: Women in Heart Valve Disease
Veulemans V, Billaud M, Nunes MCP, Goettsch C, Aikawa E. 2023 Mar 13;10:1150169. PMID: 36994000. PMC10041336. View Article
Sortilin Enhances Fibrosis and calcification in Aortic Valve Disease by Inducing Interstitial Cell Heterogeneity
Iqbal F, Schlotter F, Becker-Greene D, Lupieri A, Goettsch C, Hutcheson JD, Rogers MA, Itoh S, Halu A, Lee LH,…
Network-Guided Multiomic Mapping of Aortic Valve Calcification
Blaser MC, Kraler S, Lüscher TF, Aikawa E. Arterioscler Thromb Vasc Biol. 2023 Mar;43(3):417-26. PMID: 36727519. PMC9975082. View Article
Editorial: Extracellular Vesicles in Cardiovascular Inflammation and Calcification
Krohn JB, Aikawa E, Aikawa M, Hutcheson JD, Sahoo S, Fish JE. Cardiovasc Med. 2022 Nov 8;9:1077124. PMID: 36426218. PMC9680153.…
Editorial: Insight in Heart Valve Disease: 2021
Iop L, Chester AH, Sampaio RO, Aikawa E. Front Cardiovasc Med. 2022 Aug 26;9:998862. PMID: 36093133. PMC9459379. View Article