Rheumatic Heart Valve Disease Pathophysiology and Underlying Mechanisms
Passos LSA, Nunes MCP, Aikawa E. Front Cardiovasc Med. 2021 Jan 18;7:612716. PMID: 33537348. PMC7848031. View Article
ApoC-III Is a Novel Inducer of Calcification in Human Aortic Valves
Schlotter F, de Freitas RCC, Rogers MA, Blaser MC, Wu PJ, Higashi H, Halu A, Iqbal F, Andraski AB, Rodia CN, Kuraoka S, Wen JR, Creager M, Pham T, Hutcheson JD, Body SC, Kohan AB, Sacks FM, Aikawa M, Singh SA, Aikawa E. J Biol Chem. Jan-Jun 2021;296:100193. PMID: 33334888. PMC7948477. View Article
2020 Jeffrey M. Hoeg Award Lecture: Calcifying Extracellular Vesicles as Building Blocks of Microcalcifications in Cardiovascular Disorders
Aikawa E, Blaser MC. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):117-27. PMID: 33115271. PMC7832175. View Article
Calcific Aortic Valve Disease “Omics” Is Timely, But Are We Looking Too Late?
Atkins SK, Singh SA, Aikawa E. JACC Basic Transl Sci. 2020 Dec 28;5(12):1178-80. PMID: 33427821. PMC7775952. View Article
Mitral Regurgitation After Percutaneous Mitral Valvuloplasty: Insights Into Mechanisms and Impact on Clinical Outcomes
Nunes MCP, Levine RA, Braulio R, Pascoal-Xavier MA, Elmariah S, Gomes NFA, Soares JR, Esteves WAM, Zeng X, Dal-Bianco JP, Passos LSA, Passaglia LG, Ribeiro VT, Gelape CL, Costa PHN, Lodi-Junqueira L, Dutra W, Tan TC, Aikawa E, Hung J. JACC Cardiovasc Imaging. 2020 Dec 16;13(12):2513-26. PMID: 32950446. PMC7861508. View Article
Raising Awareness for Rheumatic Mitral Valve Disease
Passos LSA, Nunes MCP, Zilla P, Yacoub MH, Aikawa E. Glob Cardiol Sci Pract. 2020 Nov 30;2020(2):e202026. PMID: 33426043. PMC7768627. View Article
In Situ Remodeling Overrules Bioinspired Scaffold Architecture of Supramolecular Elastomeric Tissue-Engineered Heart Valves
Uiterwijk M, Smits AIPM, van Geemen D, van Klarenbosch B, Dekker S, Cramer MJ, van Rijswijk JW, Lurier EB, Di Luca A, Brugmans MCP, Mes T, Bosman AW, Aikawa E, Gründeman PF, Bouten CVC, Kluin J. JACC Basic Transl Sci. 2020 Nov 25;5(12):1187-206. PMID: 33426376. PMC7775962. View Article
Heart Valve Disease: Challenges and New Opportunities
Bartoli-Leonard F, Aikawa E. Front Cardiovasc Med. 2020 Oct 22;7:602271. PMID: 33195488. PMC7642276. View Article
An (Auto)Taxing Effort to Mechanistically Link Obesity and Calcific Aortic Valve Disease
Rogers MA, Aikawa E. JACC Basic Transl Sci. 2020 Sep 28;5(9):898-900. PMID: 33016951. PMC7524779. View Article
Annexin A1-dependent Tethering Promotes Extracellular Vesicle Aggregation Revealed with Single-Extracellular Vesicle Analysis
Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E. Sci Adv. 2020 Sep 16;6(38):eabb1244. PMID: 32938681. PMC7494353. View Article