Tissue Formation and Host Remodeling of an Elastomeric Biodegradable Scaffold in an Ovine Pulmonary Leaflet Replacement Model
Machaidze Z, D'Amore A, Freitas RCC, Joyce AJ, Bayoumi A, Rich K, Brown DW, Aikawa E, Wagner WR, Sacks MS, Mayer…
Major Facilitator Superfamily Domain Containing 5 Inhibition Reduces Lipoprotein(a) Uptake and Calcification in Valvular Heart Disease
Rogers MA, Bartoli-Leonard F, Zheng KH, Small AM, Chen HY, Clift CL, Asano T, Kuraoka S, Blaser MC, Perez KA,…
Valvulogenesis of a Living, Innervated Pulmonary Root Induced by an Acellular Scaffold
Yacoub MH, Tseng YT, Kluin J, Vis A, Stock U, Smail H, Sarathchandra P, Aikawa E, El-Nashar H, Chester AH,…
CardioVision: A Fully Automated Deep Learning Package for Medical Image Segmentation and Reconstruction Generating Digital Twins for Patients With Aortic Stenosis
Rouhollahi A, Willi JN, Haltmeier S, Mehrtash A, Straughan R, Javadikasgari H, Brown J, Itoh A, de la Cruz KI,…
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves
Ho YC, Geng X, O'Donnell A, Ibarrola J, Fernandez-Celis A, Varshney R, Subramani K, Azartash-Namin ZJ, Kim J, Silasi R,…
Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis
Blaser MC, Buffolo F, Halu A, Turner ME, Schlotter F, Higashi H, Pantano L, Clift CL, Saddic LA, Atkins SK,…
Single-Cell T Cell Receptor Sequencing of Paired Tissue and Blood Samples Reveals Clonal Expansion of CD8+ Effector T Cells in Patients With Calcific Aortic Valve Disease
Bartoli-Leonard F, Chelvanambi S, Pham T, Turner ME, Blaser MC, Caputo M, Aikawa M, Pang A, Muehlschlegel J, Aikawa E.…
Editorial: New Insights in Heart Valve Disease 2022
Greco E, Vinciguerra M, Sampaio R, Aikawa E. Front Cardiovasc Med. 2023 Jun 21;10:1226113. PMID: 37416925. PMC10321655. View Article
The Contribution of Amyloid Deposition in the Aortic Valve to Calcification and Aortic Stenosis
Sud K, Narula N, Aikawa E, Arbustini E, Pibarot P, Merlini G, Rosenson RS, Seshan SV, Argulian E, Ahmadi A,…
Editorial: Women in Heart Valve Disease
Veulemans V, Billaud M, Nunes MCP, Goettsch C, Aikawa E. Front Cardiovasc Med. 2023 Mar 13:10:1150169. PMID: 36994000. PMC10041336. View…
Sortilin Enhances Fibrosis and calcification in Aortic Valve Disease by Inducing Interstitial Cell Heterogeneity
Iqbal F, Schlotter F, Becker-Greene D, Lupieri A, Goettsch C, Hutcheson JD, Rogers MA, Itoh S, Halu A, Lee LH,…
Network-Guided Multiomic Mapping of Aortic Valve Calcification
Blaser MC, Kraler S, Lüscher TF, Aikawa E. Arterioscler Thromb Vasc Biol. 2023 Mar;43(3):417-26. PMID: 36727519. PMC9975082. View Article